CORDIS Project
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This project focuses on the structural analysis of intraflagellar transport, a process essential for cilia function in various organisms. By using advanced microscopy techniques, it aims to uncover the molecular mechanisms behind cilia assembly and transport.
Cilia are highly conserved eukaryotic organelles that, with the exception of fungi and higher plants are present in nearly all types of organisms from protists to mammals.
Through their motility, sensory, and signaling functions cilia play crucial roles in human physiology and development.
Defects in cilia have profound impact on human health.
Cilia assembly requires a dedicated protein shuttle, intraflagellar transport (IFT), a bidirectional motility of multi-megadalton protein arrays along cil…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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