CORDIS Project
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This project explores the role of different macrophage subtypes in cancer progression and their impact on the extracellular matrix. By utilizing advanced experimental techniques, it aims to clarify how these immune cells contribute to tumor growth and metastasis, potentially guiding new cancer therapies.
Solid tumors consist of malignant cancer cells in constant interaction with the extracellular matrix and different types of non-malignant cells.
Notably, these cells include macrophages which, during cancer progression, take part in an extensive degradation of the extracellular matrix.
This process leads to destruction of the normal tissue and facilitates metastatic spread.It is now evident that tumor-infiltrating macrophages have a strong impact on cancer progression and this has led to the sug…
KOBENHAVNS UNIVERSITET
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