CORDIS Project
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This project explores the three-dimensional shapes of viral capsid proteins and their structural transitions during maturation. By applying mathematical theories, it aims to enhance understanding of viral structures, which is crucial for developing antiviral drugs and self-assembling containers for drug delivery.
This project in Mathematical Biology addresses two important questions concerning the structure and life cycle of viruses: -) The classification of the possible three-dimensional shapes of the capsid proteins compatible with icosahedral
symmetry (the most common symmetry of viral capsids) by means of group theory and tiling theory; -) The modeling and prediction of the structural transitions of the viral capsids (protein containers encapsidating the genome) involved in the
maturation of the vira…
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