CORDIS Project
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This project aims to enhance drug delivery to solid tumors by utilizing macrophages to transport ferritin-encapsulated drugs directly to hypoxic tumor regions. The approach focuses on improving the effectiveness of cancer therapy while minimizing side effects through targeted drug activation in tumor-specific condition…
The proposed project seeks to open a new research front within the field of drug delivery to the solid tumours.
Unsatisfactory response of tumours to chemotherapy is mainly related to impaired diffusion of the anticancer drug because of decreased drug uptake due to poor vasculature.
Moreover, the drug is not able to penetrate the most hypoxic sites.
Cells from these ‘untreated’ sites are responsible for relapse and metastasis.
However, these avascular regions attract macrophages that migrate eve…
SGGW WARSAW UNIVERSITY OF LIFE SCIENCES
SZKOLA GLOWNA GOSPODARSTWA WIEJSKIEGO
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