CORDIS Project
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This project investigates the mechanisms affecting Th17 cell trafficking in the context of HIV and SIV infections. It aims to understand how chronic immune activation impacts these immune cells, contributing to disease progression and informing vaccine development.
More than 25 years after the discovery of human immunodeficiency virus (HIV) as the causative agent of AIDS, the mechanisms governing pathogenesis and disease progression are still not fully understood.
Indeed, a progressive impairment of the immune system, with alterations that affect both innate and adaptive immunity, characterizes the infection with HIV 1 in humans and with simian immunodeficiency virus (SIV) in macaques.
It has been proposed that a state of chronic immune activation contribu…
FONDAZIONE PER L'ISTITUTO DI RICERCA IN BIOMEDICINA
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