CORDIS Project
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This project investigates how specific neuron types in the medial entorhinal cortex and hippocampus contribute to spatial memory and the progression of Alzheimer's Disease. The research utilizes advanced genetic technology to manipulate neuronal inputs and assess their effects on memory performance.
Our memories are arguably what make us who we are, making dementia a particularly cruel disease.
Decades of research have revealed that two interconnected brain regions, the medial entorhinal cortex (MEC) and hippocampus (HP), are required for successful spatial memory formation in mammals.
Each region contains specialized neurons that fire relative to the animal`s position in physical space: grid cells in the MEC have regularly-repeating spatial firing fields throughout the entire environment (…
NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
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