CORDIS Project
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This research explores apoptosis-induced proliferation, a process where dying cells stimulate neighboring cells to divide. It aims to understand the mechanisms involved and their implications for tissue regeneration and cancer therapy.
Apoptosis-induced proliferation (AiP) is a recently discovered biological process that apoptotic cells are able to stimulate neighbouring cells to undergo additional proliferation.
Studies in several model organisms including mammals have suggested that AiP is evolutionary conserved, and may have relevance to both tissue regeneration and tumourigenesis.
Intriguingly, caspases, the proteases that normally execute apoptosis, have been implicated to play key roles in AiP through activation of their…
THE UNIVERSITY OF BIRMINGHAM
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