CORDIS Project
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This project explores the mechanisms of asymmetric cell division in mammalian brain development, particularly in the neocortex. It aims to identify factors that regulate this process and their implications for human cortical development and associated disorders.
Neurogenesis in the mammalian neocortex depends upon asymmetric cell divisions to maintain a balance between self-renewal and neuronal differentiation.
This process is likely a key element governing the expansion of the human cerebral cortex, and its disruption can lead to severe developmental disorders such as microcephaly and lissencephaly.
However, mechanisms of asymmetric cell division in mammalian brain development are largely unclear, and its potential role in human cortical development ha…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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