CORDIS Project
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This project investigates the relationship between DNA replication and meiotic recombination using the fission yeast model. It aims to understand how changes in origin usage during DNA synthesis affect genetic material exchange, which has implications for cell growth and cancer.
The control of genome duplication is critical for proper cell growth and proliferation.
Errors in DNA synthesis and defects in genome maintenance have been linked to many human diseases such as cancer.
In eukaryotes, replication initiates at sites located throughout the genome called origins, whose activation and distribution define the program of DNA replication.
However, while changes in this pattern of replication have been observed in Xenopus and Drosophila during development, in differentia…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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