CORDIS Project
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This project studies megakaryocytes, the cells responsible for producing platelets, using advanced imaging and genetic techniques. By understanding the mechanical and biological processes involved in platelet formation, the research aims to develop new therapies and improve platelet production methods, addressing criti…
Homeostatic platelet counts are crucial for vascular integrity and vital to life.
Megakaryocytes (MEKs) are giant hematopoietic cells forming large protrusions that fragment to constantly replenish the circulating platelet pool.
Nevertheless, severe blood loss, sepsis and aggressive cancer therapies, often cause critically low platelet levels - a major public health problem in Europe's aging population.
Despite the unmet clinical need to control platelet production, there is a major lack of know…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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Germany, Munchen
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
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