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The MEMETic project aims to revolutionize osteoporosis research by creating advanced models that replicate the mechanical environment of human bone. This innovative approach seeks to enhance understanding of bone disease and develop more effective therapies by integrating biological and mechanical factors.
Despite immense efforts to develop therapies for osteoporosis, conventional drugs that target bone loss only prevent osteoporotic fractures in 50% of sufferers, and the worldwide economic burden of treatment is projected to reach $132 billion by 2050.
Recently our research has (1) identified important tissue-level changes in osteoporotic bone and (2) provided evidence that the biological mechanisms by which the cells normally respond to their mechanical environment are altered.
However, no exist…
UNIVERSITY OF GALWAY
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