CORDIS Project
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This project investigates how membrane-less organelles, specifically biomolecular condensates, interact with membrane-bound organelles. By studying synaptic vesicle condensates, the project aims to uncover the molecular mechanisms underlying these interactions, which are crucial for cellular function and may relate to…
Liquid-liquid phase separation is a major mechanism for organizing macromolecules, particularly proteins with intrinsically disordered regions, in compartments not limited by a membrane.
Many such compartments (also known as biomolecular condensates) have been described, and it is currently agreed that they take over several cellular functions.
To do so, they need to interact with other compartments, just as the membrane-bound organelles interact with each other through well-defined contact site…
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