CORDIS Project
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This project aims to enhance ecological risk assessment by developing mechanistic models that predict critical internal concentrations of various chemicals from external effect data. It focuses on improving the accuracy and relevance of assessments while reducing reliance on experimental animals.
A key challenge facing environmental risk assessors is the need to assess the risk of thousands of chemicals, for a wide range of species, with increased accuracy and ecological relevance, while using fewer resources and experimental animals.
Traditional external toxicity metrics, such as the lethal aqueous concentration (LC50), are not sufficiently sophisticated to accomplish this task, and “new” approaches are emerging.
This includes the tissue residue approach (TRA), which is advocated as a p…
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