CORDIS Project
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This project explores the development of new fluorescent protein sensors that utilize the anisotropic properties of fluorophores. By anchoring these proteins to cell membranes, the project aims to create genetically encoded sensors for studying membrane protein activity and structure, enhancing our understanding of cel…
The discovery of the green fluorescent protein (GFP), and its applications have revolutionized many fields of life sciences.
The GFP (and other fluorescent proteins, XFPs) have now been used as a basis for development of optical sensors of a wide range of cellular properties and processes.
In order to convert changes in cellular properties into an optically detectable signal, the currently used probes exploit only one mechanism: environment-induced changes of the optical properties of the fluo…
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