CORDIS Project
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This project focuses on glucose transport mechanisms in mammals, specifically the SLC2A family of transporters. It aims to uncover the physiological roles and molecular interactions of these transporters to better understand their impact on metabolism and diabetes.
From molds to mammals, glucose is the most important fuel for life on earth.
The rate-limiting step for the utilization of glucose is its uptake into cells.
Mammals have fourteen different sugar transporters belonging to the SLC2A family, referred to as GLUTs. GLUT1-14 transporters have varied tissue expression and kinetics, and their activities must be synchronized and regulated for the appropriate whole-organism-wide distribution of glucose and other sugars.
Even at the most basic level, we st…
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