CORDIS Project
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This project focuses on the role of myosin-VI in the trafficking of neurotransmitter receptors in neurons, particularly in Purkinje cells. The research aims to elucidate the mechanisms of receptor movement and its implications for neuronal function and neurodegenerative diseases.
The proper trafficking of membranes and associated proteins in neurons is crucial for the function of the nervous system.
Myosin-VI is an actin-based cytoskeletal motor that promotes membrane trafficking and is suggested to play crucial roles in neurons.
Most notably, the myosin affects the intracellular trafficking of AMPA receptors, major neurotransmitter receptors composed of transmembrane protein subunits.
In addition, data suggest a potential link between myosin-VI and neurodegenerative dis…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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