CORDIS Project
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This research investigates the role of the mesentery during pregnancy and lactation, focusing on how it remodels alongside the intestine. By studying molecular signals and tissue changes in mice, the project aims to uncover the mesentery's physiological functions and developmental potential.
Reproduction involves significant resizing of many maternal organs, including the intestine.
While previous studies indicate that maternal gut growth supports offspring viability, contributions of surrounding tissues remain largely unexplored.
The mesentery–a continuous, fan-shaped peritoneal fold anchoring the intestine to the body cavity–is composed of two layers of mesothelial cells encasing a complex stroma.
Although essential during intestinal development, the adult mesentery is largely reg…
THE FRANCIS CRICK INSTITUTE LIMITED
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