CORDIS Project
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META-CHIP aims to develop a lung metastasis-on-a-chip model for osteosarcoma, a severe bone cancer in children. This innovative platform will enhance drug development by mimicking the tumor microenvironment and predicting patient responses to therapies in real-time.
Osteosarcoma is a highly aggressive bone cancer that primarily affects children.
Secondary lung metastasis is the most critical clinical factor, with 70% of those who develop lung metastasis succumbing to the disease within 3 years.
Despite the resonating clinical urgency for newer, more effective treatment options, there have been no changes in treatment since the introduction of chemotherapy in the 1970s.
Furthermore, osteosarcoma is a rare disease making the conduct of large clinical trials i…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
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