CORDIS Project
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This project investigates how reactive oxygen species (ROS) influence DNA replication and cell cycle dynamics during early development and cancer. By utilizing advanced techniques, it aims to uncover the mechanisms linking metabolic fluctuations to genome integrity, providing insights into cellular regulation and poten…
Metabolic fluctuations and changes in DNA replication and cell cycle dynamics orchestrate early development and tumorigenesis.
Of particular interest are reactive oxygen species (ROS), by-products of basal metabolic reactions, and major signaling molecules driving cell proliferation, differentiation, and cancer cell growth.
However, despite their utmost importance in cell physiology, how ROS signals communicate to the cell cycle and genome safeguard mechanisms remains poorly explored.
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SYDDANSK UNIVERSITET
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