CORDIS Project
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This project investigates the role of conventional dendritic cells in non-alcoholic fatty liver disease and its progression to non-alcoholic steatohepatitis. By examining the relationship between immune responses and metabolic changes in the liver, the research aims to uncover new insights into disease mechanisms and p…
Non-alcoholic fatty liver disease (NAFLD) is a major global health problem with no approved treatments, and dire outcomes for patients.
The pathogenesis of NAFLD is clearly linked to metabolic alterations, and is primarily characterized by excessive hepatic triglyceride content.
Over time, metabolic dysfunction induces hepatic inflammation through mechanisms that remain poorly understood.
This advanced disease stage, called non-alcoholic steatohepatitis (NASH), significantly raises the risk of h…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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