CORDIS Project
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This project investigates how essential metabolic pathways could have emerged from geochemical reactions mediated by transition metals, without the need for enzymes. It aims to explore the spontaneous formation of biosynthetic pathways for vital biological molecules, providing insights into the origins of life and the…
It has long been assumed that biological metabolism must have been an invention of life since its many reactions are catalyzed by enzymes, complex proteins that did not exist at lifes origins.
However, my group and others have recently discovered that transition metals alone can mediate reactions of lifes most central metabolic pathways in the absence of enzymes (Wood-Ljungdahl pathway, glycolysis, parts of the Krebs cycle and reverse Krebs cycle, etc.).
In contrast to ideas about the origin of…
Université de Strasbourg - FRC
CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIERES DE LA CHIMIE FONDATION
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France, Strasbourg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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