CORDIS Project
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This project investigates the role of microRNAs in regulating gene expression related to metabolic disorders like obesity and type 2 diabetes. It aims to identify specific microRNA networks in tissues and develop methods for targeted delivery of RNA-based therapies to improve metabolic health.
Small RNA-mediated regulation of gene expression is a recent addition to fundamental gene regulatory mechanisms that directly or indirectly affect possibly every gene of a eukaryotic genome.
The predominant sources of small RNA in somatic tissues are microRNA genes that encode short dsRNA hairpins of evolutionary conserved sequence.
Disorders of metabolism, such as obesity and type 2 diabetes are poorly understood at a molecular level.
In this application we propose to explore if miRNA regulator…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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