CORDIS Project
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This project investigates the role of specific muscle cells in intestinal repair and regeneration, particularly focusing on the enzyme Mmp17. It aims to understand how these cells contribute to healing after injury and their potential implications for treating gastrointestinal diseases and cancers.
The digestive tract has been assigned important but complex tasks.
It provides our body with nutrients and water.
It gets rid of pathogens while allowing the commensal flora to thrive, and it quickly repairs injuries caused by the constant mechanical and biological stress.
Lgr5+ intestinal stem cells (ISCs) play a crucial role in these processes, but when ISCs are lost due to injury, differentiating cells must ‘de-differentiate’ into ISCs to regain the stem cell pool.
The cellular signalling pro…
NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU
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