CORDIS Project
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This project investigates the role of blood vessel types in regulating dormant tumor cells in bone, particularly how age-related factors influence this process. It employs advanced imaging and genetic techniques to explore the links between vascular aging and cancer metastasis.
Blood vessels form a versatile transport network and provide inductive signals called angiocrine factors to regulate tissue-specific functions.
Blood vessels in bone are heterogeneous with distinct capillary subtypes that exhibit remarkable alterations with age.
Bone is the most prevalent site of metastasis, and ageing is linked to the reactivation of dormant tumor cells (dorTCs) and metastatic relapse.
Bone remodeling processes are also associated with metastatic relapse.
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United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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