CORDIS Project
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This project seeks to develop transition-metal catalyzed reactions that can occur in living cells, aiming to create targeted therapeutic strategies and bio-sensing tools. It focuses on delivering catalytic activity to specific cellular sites.
This proposal aims at the discovery of robust transition-metal catalyzed transformations that can take place in aqueous media and cellular lysates, and are susceptible of being exported to living cells.
Specifically, we will exploit the special coordination and activation ability of different metal complexes towards pi-systems to induce chemo-selective reactions of designed, abiotic, unsaturated substrates.
Moreover, and importantly, the metal catalysts will be conjugated to designed ligands or…
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
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