CORDIS Project
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This project investigates how metabolism influences the behavior of pluripotent stem cells, which can develop into any cell type. It aims to understand the interplay between metabolism, gene expression, and epigenetics to enhance regenerative medicine applications.
Pluripotent Stem cells (PSCs) can give rise to all differentiated cells of the body and the germ line, which makes them conceptually fascinating and a valuable tool for regenerative medicine.
Mouse PSCs are devoid of any developmental restriction partly thanks to their “open” chromatin, characterised by remarkably low levels of repressive epigenetic modifications.
Metabolism is a key feature that can be adjusted to meet the cell’s needs, and that has the potential to feedback on transcription an…
UNIVERSITA DEGLI STUDI DI PADOVA
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