CORDIS Project
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This project investigates how gut microbes influence the formation of blood vessels in the intestine. By studying germ-free and conventionally raised mice, the research aims to identify specific molecules that promote vascular development, which could have implications for understanding intestinal health and diseases l…
Objective:
The mammalian gut is colonized by trillions of bacteria.
These gut microbes (microbiota) have coevolved with the host and developed traits that affects host physiology.
Interestingly, germ-free (GF) mice exhibit arrested intestinal vascularisation if compared to littermates that were raised in a non-sterile environment (CONV-R, conventional-raised).
Intestinal colonization with a normal microbiota initiates massive formation of capillary networks in the intestine of ex-GF mice (CONV-D…
UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
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KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT
Germany, Wurzburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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