CORDIS Project
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This project develops a novel computational framework to model therapeutic resistance in triple negative breast cancer. By integrating gene networks and agent-based modeling, it aims to predict effective drug combinations and improve treatment strategies for this challenging cancer type.
The occurrence of therapeutic resistance is a major cause for the small effect on overall survival showed by targeted cancer therapies.
Whilst experimental strategies to evaluate available treatments have been faced by an ever increasing number of possible combinations, computational approaches have been challenged by the lack of a framework able to model the multiple interactions encompassed by the three major factors affecting therapeutic resistance: selection of resistant clones, adaptability…
UNIVERSITA COMMERCIALE LUIGI BOCCONI
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United Kingdom, Oxford
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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