CORDIS Project
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This project focuses on advancing microcrystallography techniques to determine the high-resolution structure of the beta-adrenergic receptor and other membrane proteins. By utilizing microfocus beamlines and developing new data collection methods, it aims to enhance our understanding of G protein-coupled receptor signa…
Nowadays microfocus beamlines at intense and brilliant synchrotron radiation sources allow studies of samples with low X-ray scattering power to be curried out with new micro-methods.
Structural information of excellent quality can be produced for proteins, which crystallize yielding only tiny crystals.
The structure of recombinant rhodopsin obtained recently in host laboratory is an example of successful microcrystallography application.
Several other membrane proteins from the GPCR family were…
MEDICAL RESEARCH COUNCIL
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