CORDIS Project
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This project develops a more accessible method for hyperpolarized magnetic resonance imaging to study human muscle tissue, specifically focusing on muscular dystrophy. By using parahydrogen-induced polarization and organ-on-a-chip devices, it aims to enhance metabolic imaging capabilities and reduce reliance on animal…
Hyperpolarized (HP) magnetic resonance imaging has emerged as a promising method for probing the biological characteristics of living tissue. A sensor molecule (e.g. pyruvate, fumarate, acetate) is hyperpolarized and injected into a patient, and the resulting metabolic flux can be used to assess cell viability, tumour response to therapy, and perform pH mapping, to name a few examples.
Two significant barriers stand in the way of the widespread implementation of HP imaging: (1) the current hyper…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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