CORDIS Project
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This project investigates the role of reactive oxygen species in calcium signaling within heart cells after myocardial infarction. It aims to identify molecular targets for diagnosing and potentially reversing heart remodeling.
An increasing number of people suffer cardiovascular diseases and experience myocardial infarction (MI).
The subsequent heart remodeling is characterized by weaker contractility, hypertrophy and lethal arrhythmias.
The poorly-understood underlying mechanism is related to calcium (Ca2+) mishandling in cardiomyocytes and oxidative stress.
To date, most of the studies described global cellular processes and were unable to propose efficient therapies.
This work will decipher the structural and funct…
KATHOLIEKE UNIVERSITEIT LEUVEN
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