CORDIS Project
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MicroTher focuses on the clinical potential of indole-3-aldehyde, a molecule that helps restore the integrity of the intestinal lining. This project aims to evaluate its feasibility as a treatment for conditions like metabolic syndrome and inflammatory bowel syndrome.
The rapid increase in the prevalence of diseases caused by the disruption of the intestinal epithelium, also known as leaky gut syndrome, is a global cause for concern.
Metabolic syndrome (MetSyn) and inflammatory bowel syndrome (IBS), two disease indications that occur as a result of a compromised intestinal mucosal membrane, collectively effect over 235 million people globally.
In a healthy gut, the epithelial lining is tightly aligned to form a structurally robust barrier between the outside…
UNIVERSITA DEGLI STUDI DI PERUGIA
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