CORDIS Project
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This project investigates the effects of reducing leptin levels in obese individuals to enhance sensitivity to leptin, aiming to improve weight loss and metabolic health. By exploring the molecular mechanisms behind this response, the research seeks to establish partial leptin reduction as a potential treatment for obe…
Leptin regulates energy balance by functioning as a “satiety signal”.
When identified 26 years ago, expectations were high that leptin therapies could be used for the treatment of obesity.
In contrast to the successful use of leptin for treatment of individuals with lipodystrophy and complete leptin deficiency, pharmacological approaches using leptin therapy for the treatment of diet-induced obesity have been widely unsuccessful.
Injecting recombinant leptin in the context of obesity, associated…
UNIVERSITETET I BERGEN
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THE UNIVERSITY OF TEXAS SYSTEM
United States, Austin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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