CORDIS Project
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This project explores the role of sensory cilia in C. elegans, focusing on how they facilitate chemotaxis through intracellular transport mechanisms. It aims to develop imaging techniques to study the dynamics of cilia and their response to environmental cues.
Sensory cilia are essential ‘antenna-like’ organelles that protrude out of many eukaryotic cells, acting as signal transducers, enabling cells to sense and respond to the external environment.
The model system for this proposed study, chemosensory cilia of C. elegans are well characterised and enable the animal to sense water soluble effectors in the environment for chemotaxis.
Cilia consist of an axoneme encapsulated with a signalling protein-rich ciliary membrane.
The axoneme, which is a micro…
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