CORDIS Project
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This project develops calcium phosphate nanoparticles for targeted delivery of microRNA-133 to treat cardiac hypertrophy. By enhancing delivery efficiency, the project aims to create a novel therapeutic strategy for cardiovascular diseases.
Innovative nanoparticle formulation for a miR-133 based treatment of cardiac hypertrophyCardiovascular diseases (CDs) are growing problems worldwide, affecting as much as 1% of the population.
The causes include ischemic, toxic, genetic, post-inflammatory and structural defects; often multiple etiologies are present within an individual patient germane to the contraction failing, resulting in a mortality of ca. 50% within 5 years from diagnosis.
Unexpected roles have been unveiled for microRNAs,…
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