CORDIS Project
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This research investigates the role of microRNAs in gene regulation, focusing on their potential functions beyond silencing targets. By developing a new method to analyze microRNA interactions at the single-cell level, the project aims to uncover novel insights into gene expression and its implications for health.
It is now becoming apparent that genes are regulated not only by transcription, but also by thousands of post-transcriptional regulators that can stabilize or degrade mRNAs.
Some of the most important regulators are miRNAs, short RNA molecules that are deeply conserved in sequence and are involved in numerous biological processes, including human disease.
Surprisingly, transcriptomic and proteomic studies show that most miRNAs only have subtle silencing effects on their targets, suggesting addit…
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