CORDIS Project
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This project focuses on neuroblastoma, a common childhood cancer, aiming to restore microRNA levels to combat tumor aggressiveness and chemotherapy resistance. It involves developing nanoparticle-based therapies and assessing microRNA as potential biomarkers for treatment response.
Neuroblastoma (NBL) is the most common solid tumor of infancy.
Nearly 45% of all children with NBL are designated as high-risk patients and 60% of them die.
Therefore, there is an urgent need to identify and target the molecular programs that are responsible for NBL aggressiveness, especially those that contribute to metastasis and resistance to chemotherapy.Recently, it has become evident that microRNAs (miRNAs) are deregulated in numerous diseases including cancer.
Particularly in NBL, there i…
FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA
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