CORDIS Project
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This project investigates the role of microRNAs in tooth development and dental stem cells. By employing advanced bioinformatics and molecular biology techniques, it aims to uncover the regulatory mechanisms that govern gene expression during the formation of teeth and other ectodermal organs, contributing to tissue re…
Teeth form as appendages of embryonic ectoderm and their development is regulated by similar mechanisms to other ectodermal organs like hairs and glands.
More than 300 genes are currently known to be involved in tooth development.
However, the mechanisms that regulate gene expression at specific times and locations are only partially understood.
The most interesting open questions concern the mechanisms of the initial acquisition of organ specificity and the regulation of stem cells. microRNAs (…
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