CORDIS Project
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This project investigates microRNAs (miRNAs) in C. elegans to understand their role in gene regulation. By using advanced genetic screening techniques, it aims to identify miRNA targets and their interactions within genetic networks, contributing to our knowledge of miRNA functions in development and disease.
MicroRNAs (miRNAs), a large class of ~22 nucleotide non-coding RNAs (sRNAs) found in many plants and animals act to post-transcriptionally regulate gene expression.
Approximately 3% of all known human genes encode miRNAs.
Important functions for miRNAs in development, physiology and disease are emerging.Here we propose to identify and characterize miRNA genetic networks by combining forward and reverse genetic approaches, experimental target identification, quantitative cell biology and computat…
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