CORDIS Project
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This research focuses on understanding the role of microRNAs in gene regulation, particularly their post-transcriptional regulation in cell differentiation. Using the model organism C. elegans, it aims to identify factors that influence microRNA expression patterns and their contribution to cellular diversity.
MicroRNAs are versatile regulators of gene expression and as such, they are essential parts of the gene regulatory networks controlling development and physiology of animals and plants.
In particular, a number of miRNAs have been implicated in cell-type differentiation.
Adding miRNAs to existing networks in particular subsets of cells can increase the complexity of developmental programs, and thus contribute to the vast diversity of cell types found in complex multicellular organisms.In order to…
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