CORDIS Project
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This project investigates the interactions between microbes and host responses in cystic fibrosis patients using samples of exhaled breath. By applying metabolomics techniques, it aims to understand the chemical environment in the lungs and improve personalized treatment strategies for pulmonary exacerbations.
Cystic fibrosis (CF) is a lethal genetic disease affecting 1 out of 2500 newborns.
In CF patients, compromised innate immunity enhances the susceptibility to colonization of lower airways by different microbes, leading to long-term bacterial infections.
Data suggests that the resulting host-pathogen interactions can shape the course of disease progression, but this relationship is still poorly understood. I propose to use CF patients' samples of exhaled breath condensate to investigate intra-mic…
UNIVERSITE GRENOBLE ALPES
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United States, East Lansing, Michigan
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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