CORDIS Project
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This project explores the regulation of steroid hormone production in zebrafish, focusing on the role of cofactors in steroidogenic enzymes. By studying disrupted steroidogenesis, it aims to uncover mechanisms that could inform treatments for related health issues.
Steroid hormones to control sex development, metabolism, stress response, blood pressure and body composition.
Steroid hormones synthesis and action is conserved across species.
The importance of cofactors in the function of steroidogenic enzymes has become apparent during recent years.
Data from in vitro research suggests important regulatory capacity of co-factors significantly influencing total steroid hormone production.
However, the significance of these mechanisms in vivo remains elusive.…
THE UNIVERSITY OF BIRMINGHAM
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