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MitO2Health investigates Major Depressive Disorder as a systemic energy deficiency, focusing on mitochondrial dysfunction and its impact on mental health. The project aims to establish a new model for understanding depression and to explore the effectiveness of cognitive-behavioral therapy in improving biological marke…
MitO2Health aims to develop and empirically prove a radically new pathophysiological model of Major Depressive Disorder (MDD) as a systemic energy deficiency disease.
Traditionally, MDD is conceptualized as a neurotransmitter deficiency in the brain.
However, with pioneering methods my group has provided evi-dence for reduced mitochondrial energy production in MDD, characterizing it as a cellular-metabolic disorder with a lowered production of adenosine triphosphate (ATP).
Reduced mitochondrial…
UNIVERSITAET ULM
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