CORDIS Project
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This project investigates the mechanisms of ischemia-reperfusion injury in acute myocardial infarction and evaluates a new therapy, TRO40303, aimed at reducing heart damage. By combining clinical and preclinical research, it seeks to enhance patient recovery and inform future treatment strategies.
Current interventional treatment of acute myocardial infarction (AMI) focused on re-establishing cardiac reperfusion has significantly improved clinical outcome by reducing infarct size and mortality due to cardiac ischemia.It is now recognized that events triggered at reperfusion also result in cell death and may account for as much as 50% of the infarct volume, this being termed ischemia-reperfusion injury (IRI).
Mitochondrial permeability transition pore (mPTP) opening appears to be a respons…
TROPHOS SA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France, Paris
Type: Research institute
Activity type: Research Organisations
SME: No
Norway, Bergen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Denmark, Aalborg
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
SME: No
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