CORDIS Project
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This project investigates how certain fungi evolve to become harmful to humans, particularly in immunocompromised individuals. It focuses on the role of fungal mitochondria in regulating virulence, using genetic, cellular, and imaging techniques to understand this transformation.
Fungal diseases represent a significant and growing threat to human health, particularly since the AIDS pandemic and increasing use of immunosuppressive drugs has produced a massive population of people with impaired immunity who are vulnerable to fungal infections. A great challenge in medical mycology is to understand how fungal virulence evolves.
The vast majority of fungal species are not human pathogens and, for those that are, virulence appears to have evolved independently on many differ…
THE UNIVERSITY OF BIRMINGHAM
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