CORDIS Project
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This project investigates how mitochondrial shape changes in response to nutrient availability and its impact on metabolism. It focuses on understanding the molecular mechanisms behind mitochondrial fission and fusion, particularly in heart, liver, and kidney tissues, to identify potential therapeutic targets for relat…
The need for mitochondria in the body is ubiquitous yet the shapes these organelles take vary widely across tissues and change rapidly in response to nutrient availability.
How and why this occurs is not well understood.
Therefore, we propose an interdisciplinary research program that will investigate the molecular basis and metabolic regulation of mitochondrial morphology.
Mitochondrial morphology is defined by opposing events of fission and fusion, which must be tightly controlled.
We discov…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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