CORDIS Project
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This project aims to understand the role of mitochondria in demyelinating peripheral neuropathies. By using viral vectors to manipulate mitochondrial functions in Schwann cells, the research seeks to uncover mechanisms that could lead to new treatments for these diseases.
Demyelinating peripheral neuropathies form a diverse group of pathologies that include diabetic and aging peripheral neuropathies and inherited Charcot-Marie-Tooth diseases.
Mitochondrial dysfunctions have recently emerged as one major cause for these diseases.
The goal of this project is to investigate the role of mitochondria in healthy and diseased myelin and to test whether we can change mitochondrial status and functions to prevent or treat these diseases.
Our working hypothesis is that gli…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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