CORDIS Project
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This project investigates how mitochondrial reactive oxygen species (mROS) influence cellular differentiation in the parasites Trypanosoma brucei and T. congolense. By utilizing advanced techniques, it aims to uncover the mechanisms by which mROS drive physiological responses and communicate vital signals within the ce…
Mitochondria perform three essential functions:
ATP production, metabolite synthesis and cellular signaling.
These signals, communicating the bioenergetic and biosynthetic fitness of the organelle to the nucleus, play a powerful role in determining cellular fate.
The incorporation of mitochondrial reactive oxygen species (mROS) in cellular signaling is an interesting evolutionary outcome, as excess levels of these potent oxidizers have been implicated in many pathologies.
While most research foc…
BIOLOGICKE CENTRUM AKADEMIE VID CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
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