CORDIS Project
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This project focuses on improving metal-catalyzed carbon-hydrogen bond functionalization by developing a method that eliminates the need for pre-attached directing groups. It aims to enhance selectivity and replace precious metals with more sustainable alternatives, enabling broader industrial applications in fine chem…
Transition metal-catalyzed C-H functionalization replaces an inert carbon-hydrogen bond with a functional group, expediently altering the properties of the parent molecule to access new classes of compounds.
Although the C-H functionalization represents a green chemistry approach as it precludes the need for pre-functionalized starting materials, there are still two main sustainability shortcomings with most current methodologies.
The first challenge is achieving functionalization of specific C-…
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