CORDIS Project
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This research aims to create protein-based hydrogels with improved mechanical properties for surgical applications. By leveraging molecular design principles, the project seeks to develop gels that mimic the extracellular matrix and can be used as adhesives or sealants in medical settings.
Protein-based hydrogels are commonly used as adhesives and sealants in surgical settings.
Fibrin gels, for example, are biocompatible, however their use is hampered by poor mechanical properties.
Previous attempts to improve fibrin gel mechanics relied on interpenetrating networks in combination with PEO, collagen and other polymers, however, only modest improvements were observed.
The important challenge lies in understanding how molecular design principles can influence gel mechanics on the ma…
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